Title of article
Poly(ethylene glycol) decorated poly(methylmethacrylate) nanoparticles for protein adsorption
Author/Authors
Bonfل، نويسنده , , Alfredo and Saito، نويسنده , , Rafael S.N. and França، نويسنده , , Rafael F.O. and Fonseca، نويسنده , , Benedito A.L. and Petri، نويسنده , , Denise F.S.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2011
Pages
5
From page
562
To page
566
Abstract
Poly(ethylene glycol) decorated poly(methyl methacrylate) particles were synthesized by means of emulsion polymerization using poly(ethylene glycol) sorbitan monolaurate (Tween-20) as surfactant. PMMA/PEG particles presented mean diameter (195 ± 15) nm, indicating narrow size distribution. The adsorption behavior of bovine serum albumin (BSA) and concanavalin A (ConA) onto PMMA/PEG particles was investigated by means of spectrophotometry. Adsorption isotherms obtained for BSA onto PMMA/PEG particles fitted well sigmoidal function, which is typical for multilayer adsorption. Con A adsorbed irreversibly onto PMMA/PEG particles. The efficiency of ConA covered particles to induce dengue virus quick agglutination was evaluated.
Keywords
BSA , Concanavalin A , Dengue virus , Nanoparticles , Adsorption , Poly(ethylene)glycol
Journal title
Materials Science and Engineering C
Serial Year
2011
Journal title
Materials Science and Engineering C
Record number
2101202
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