Author/Authors :
Tang، نويسنده , , Qingjuan and Li، نويسنده , , Dan and Xu، نويسنده , , Jie and Wang، نويسنده , , Jingfeng and Zhao، نويسنده , , Yuran and Li، نويسنده , , Zhaojie and Xue، نويسنده , , Changhu، نويسنده ,
Abstract :
Murine norovirus-1 (MNV) is currently the most suitable surrogate for human norovirus. The mechanism of MNV-1 inactivation by high pressure processing (HPP) was investigated. HPP-treated MNV could not bind to its target receptor and therefore could not initiate infection of mouse RAW cells. The integrity of the capsid was not affect by HPP. Partial motif changes of the viral capsid caused by HPP were accessed by induced sensitivity to proteinase K.
Keywords :
High-pressure processing , Murine norovirus-1 , Mechanism , Capsid protein
