Effect of Oxidized Fish Oil and α-Tocopherol on the Peroxidation of Erythrocyte Membrane Phospholipids in Rats

The effects of dietary oxidized fish oil and α-tocopherol on the thiobarbituric acid (TBA) values and phospholipid hydroperoxide levels of the erythrocyte membrane were studied in rats. No significant differences in the TBA values or phospholipid hydroperoxide levels of the membrane were observed between groups fed either oxidized fish oil or control diets. Furthermore, there were no marked differences in these values whether or not the groups were administered diets containing added α-tocopherol. These results suggest that the intake of oxidized fish oil and the supplementation with α-tocopherol do not influence the level of lipid peroxidation in the erythrocyte membrane.