Author/Authors :
Adams، نويسنده , , T.B. and Doull، نويسنده , , J and Feron، نويسنده , , V.J and Goodman، نويسنده , , J.I and Marnett، نويسنده , , Anthony L.J. and Munro، نويسنده , , I.C and Newberne، نويسنده , , P.M and Portoghese، نويسنده , , P.S. and Smith، نويسنده , , R.L and Waddell، نويسنده , , W.J and Wagner، نويسنده , , B.M، نويسنده ,
Abstract :
This is the fifth in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In 1993, the Panel initiated a comprehensive program to re-evaluate the safety of more than 1700 GRAS flavoring substances under conditions of intended use. Elements that are fundamental to the safety evaluation of flavor ingredients include exposure, structural analogy, metabolism, pharmacokinetics and toxicology. Flavor ingredients are evaluated individually taking into account the available scientific information on the group of structurally related substances. Scientific data relevant to the safety evaluation of the use of pyrazine derivatives as flavoring ingredients is evaluated.
Keywords :
Flavoring agents , Pyrazine derivatives , Food safety , GRAS
