• Title of article

    The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients

  • Author/Authors

    Adams، نويسنده , , T.B. and Doull، نويسنده , , J and Feron، نويسنده , , V.J and Goodman، نويسنده , , J.I and Marnett، نويسنده , , Anthony L.J. and Munro، نويسنده , , I.C and Newberne، نويسنده , , P.M and Portoghese، نويسنده , , P.S. and Smith، نويسنده , , R.L and Waddell، نويسنده , , W.J and Wagner، نويسنده , , B.M، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2002
  • Pages
    23
  • From page
    429
  • To page
    451
  • Abstract
    This is the fifth in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In 1993, the Panel initiated a comprehensive program to re-evaluate the safety of more than 1700 GRAS flavoring substances under conditions of intended use. Elements that are fundamental to the safety evaluation of flavor ingredients include exposure, structural analogy, metabolism, pharmacokinetics and toxicology. Flavor ingredients are evaluated individually taking into account the available scientific information on the group of structurally related substances. Scientific data relevant to the safety evaluation of the use of pyrazine derivatives as flavoring ingredients is evaluated.
  • Keywords
    Flavoring agents , Pyrazine derivatives , Food safety , GRAS
  • Journal title
    Food and Chemical Toxicology
  • Serial Year
    2002
  • Journal title
    Food and Chemical Toxicology
  • Record number

    2117022