Author/Authors :
Casella، نويسنده , , Tiago and Rodrيguez، نويسنده , , Marيa Margarita and Takahashi، نويسنده , , Juliana Tiemi and Ghiglione، نويسنده , , Barbara and Dropa، نويسنده , , Milena and Assunçمo، نويسنده , , Ednei and Nogueira، نويسنده , , Maurيcio Lacerda and Lincopan، نويسنده , , Nilton and Gutkind، نويسنده , , Gabriel and Nogueira، نويسنده , , Mara Corrêa Lelles، نويسنده ,
Abstract :
CTX-M-type extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae have been increasingly identified in humans and animals, and their potential transmission by contaminated food has been highlighted. In this study, we report for the first time the isolation of multidrug-resistant (MDR) Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis strains harboring blaCTXM-2 or blaCTXM-8 gene variants in chicken meat sold in markets in southeast Brazil. In this regard, the genetic environment of the blaCTX-M-2 gene is composed of a complex class 1 integron and an ISCR1-associated sequence with dfr and/or aadA gene cassettes located within the variable region. In summary, chicken meat may be a reservoir of MDR Enterobacteriaceae harboring blaCTX-M-type genes, which is a public health concern.
Keywords :
ISCR1 , CTX-M , Chicken meat , Poultry
