Author/Authors :
-، - نويسنده Department of Diagnostic Radiology and Nuclear Medicine, Tokyo Medical and Dental University, Yushima, Bunkyoku,
Tokyo, Japan Toriihara, Akira , -، - نويسنده Department of Otolaryngology, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, Japan Tsunoda, Atsunobu , -، - نويسنده Department of Human Pathology, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, Japan Takemoto, Akira , -، - نويسنده Department of Diagnostic Radiology and Nuclear Medicine, Tokyo Medical and Dental University, Yushima, Bunkyoku,
Tokyo, Japan Kubota, Kazunori , -، - نويسنده Department of Diagnostic Radiology and Nuclear Medicine, Tokyo Medical and Dental University, Yushima, Bunkyoku,
Tokyo, Japan Machida, Youichi , -، - نويسنده Department of Diagnostic Radiology and Nuclear Medicine, Tokyo Medical and Dental University, Yushima, Bunkyoku,
Tokyo, Japan Tateishi, Ukihide
Abstract :
Temporal bone chondroblastoma is an extremely rare benign bone tumor. We encountered two cases showing similar imaging findings on computed tomography (CT), magnetic resonance imaging (MRI), and dual-time-point 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/CT. In both cases, CT images revealed temporal bone defects and sclerotic changes around the tumor. Most parts of the tumor showed low signal intensity on T2- weighted MRI images and non-uniform enhancement on gadolinium contrast-enhanced T1-weighted images. No increase in signal intensity was noted in diffusion-weighted images. Dual-time-point PET/CT showed markedly elevated 18F-FDG uptake, which increased from the early to delayed phase. Nevertheless, immunohistochemical analysis of the resected tumor tissue revealed weak expression of glucose transporter-1 and hexokinase II in both tumors. Temporal bone tumors, showing markedly elevated 18F-FDG uptake, which increases from the early to delayed phase on PET/CT images, may be diagnosed as malignant bone tumors. Therefore, the differential diagnosis should include chondroblastoma in combination with its characteristic findings on CT and MRI.
