Author/Authors :
Karimi، Abdollah نويسنده , , Rafiei Tabatabaei، Sedigheh نويسنده Pediatric Infections Research Center, Department of Pediatric Infectious Diseases, Shahid Beheshti University of Medical Sciences , , Shiva، Farideh نويسنده Pediatric Infections Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences , , Sayfikar، Maryam نويسنده Pediatric Infections Research Center, Department of Pediatric Infectious Diseases, Shahid Beheshti University of Medical Sciences , , Jafari، Mohsen نويسنده Pediatric Infections Research Center, Department of Pediatric Infectious Diseases, Shahid Beheshti University of Medical Sciences , , Shirvani، Fariba نويسنده Department of Pediatrics, Pediatric Infections Research Center, Mofid Children Hospital. Shaheed Beheshti University of Medical Sciences and Health Services, Tehran, Iran , , SHIARI، Reza نويسنده MD,Ph.D,Assistant Professor of Pediatric Rheumatology,Shahid Beheshti University of Medical Sciences,Tehran,Iran ,
Abstract :
Pachymeningitis is a rare chronic disorder of the duramater caused by various infectious, autoimmune or malignant diseases. We report a child with chronic tuberculous pachymeningitis, who presented with clinical manifestations of meningitis with a compatible cerebrospinal fluid analysis. Despite signs of progressive neurological involvement, extensive work-up done to rule out known causes of dural inflammation was negative. The patient was started empirically on anti-tuberculous therapy, to which he responded after 2 weeks. He was discharged on anti-TB medications. He remains well on follow-up. We recommend a trial of anti-tuberculous treatment in children presenting with signs of pachymeningitis in whom the cause of chronic meningeal inflammation cannot be identified.
