Author/Authors :
-، - نويسنده Department of Chemistry, Shahid Beheshti University, P. O. Box 19396-4716, Tehran, I.R. IRAN Shaabani, Ahmad , -، - نويسنده Department of Chemistry, Shahid Beheshti University, P. O. Box 19396-4716, Tehran, I.R. IRAN Bazgir, Ayoob , -، - نويسنده Department of Chemistry, Shahid Beheshti University, P. O. Box 19396-4716, Tehran, I.R. IRAN Arab Ameri, Sakineh , -، - نويسنده Department of Chemistry, Shahid Beheshti University, P. O. Box 19396-4716, Tehran, I.R. IRAN Sharifi Kiasaraie, Masoumeh , -، - نويسنده Department of Chemistry, Shahid Beheshti University, P. O. Box 19396-4716, Tehran, I.R. IRAN Samadi, Sima
Abstract :
Alkali and alkaline earth metals hydrogen sulfate catalyzed the one-pot three component condensation reactions of aldehydes, 1,3-dicarbonyl compounds and urea or thiourea under solvent-free conditions leading to 3,4-dihydropyrimidin-2(1H)-ones in high yields at 80 °C. Our results showed that Biginelli reaction not only is pH dependent, but the cation of catalyst plays an important role.
