Author/Authors :
Pescovitz، نويسنده , , M.D and Book، نويسنده , , B.K and Aasted، نويسنده , , B and Dominguez، نويسنده , , J and Bullido، نويسنده , , A and Trebichavsky، نويسنده , , I and Novikov، نويسنده , , B and Valpotic، نويسنده , , I and Nielsen، نويسنده , , J and Arn، نويسنده , , S and Sachs، نويسنده , , D.H and Lunney، نويسنده , , J.K and Boyd، نويسنده , , P.C and Walker، نويسنده , , J and Lee، نويسنده , , R and Petrinec، نويسنده , , N and Saalmüller، نويسنده , , A، نويسنده ,
Abstract :
Among the 57 monoclonal antibodies analyzed within the T-cell group of the Second International Swine CD Workshop, one mAb fell within cluster T14a that included the CD6 standard a38b2 (No. 175). The new mAb MIL8 (No. 082) and a38b2 both precipitated from activated T-cells a 150 kDa monomeric protein. Staining patterns on the various cell types were similar. There was no inhibition of binding of either mAb to peripheral blood T-cells with the opposite mAb. The new mAb, MIL8, reacts with a separate epitope on porcine wCD6.