Title of article :
Leukocyte profile of cattle persistently infected with bovine viral diarrhea virus
Author/Authors :
Brewoo، نويسنده , , Joseph N. and Haase، نويسنده , , Christopher J. and Sharp، نويسنده , , Patricia and Schultz، نويسنده , , Ronald D.، نويسنده ,
Issue Information :
سالنامه با شماره پیاپی سال 2007
Pages :
6
From page :
369
To page :
374
Abstract :
Animals acutely infected with bovine viral diarrhea virus (BVDV) exhibit transient immunosuppression as a result of the virus’ predilection for cells that play critical roles in the host immune system. Acute BVDV infections have major effects on thymic and follicular T-lymphocytes, as well as follicular B-lymphocytes, often resulting in severe reduction in circulating numbers of lymphocytes and suppression of functional activities of these cells. Granulocytes and monocytes are equally susceptible to BVDV infections with reduction in numbers and suppression functions. However, there is limited information on the leukocyte profile of cattle persistently infected (PI) with BVDV. This study reports on phagocytic activities of granulocytes and monocytes as well as immunophenotyping by flow cytometric analysis of leukocytes isolated from healthy non-PI (NPI) and PI animals. No significant differences were found between the leukocyte profiles and the phagocytic activities of PI animals when compared to a group of healthy NPI animals.
Keywords :
Leukocyte profile , BVDV , Persistent infection , Phagocytosis
Journal title :
Veterinary Immunology and Immunopathology
Serial Year :
2007
Journal title :
Veterinary Immunology and Immunopathology
Record number :
2163327
Link To Document :
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