The Effect of Beclomethasone Nasal Spray on the Size of Adenoid and its Related Obstructive Symptoms in Children with Adenoid Hypertrophy.

Background: Adenoid hypertrophy is associated with high morbidity rate in children. Although surgical treatment is indicated in severe cases, however, there are evidences that some medical interventions are effective in improvement. This study was conducted to evaluate the effectiveness of beclomethasone nasal spray on reduction of airway obstruction due to adenoid hypertrophy. Methods: In a clinical trial study 31 children between the ages of 3-13 years suffering from excessive adenoid hypertrophy were administered beclomethasone nasal spray (2 puffs each 12 hr) for duration of 8-week. All subjects were evaluated for adenoid size and grade of airway obstruction before and after the intervention by lateral neck radiography. A questionnaire was filled in by subjects’ parents to assess obstructive symptoms before and after the intervention. Results: Radiographic findings revealed that after treatment adenoid size was significantly less than its size before treatment and airway diameter was significantly more than before treatment. Also finding showed that severe and moderate forms of nasal obstructive findings after intervention were significantly less frequent than before it. Conclusion: According to our research, topical nasal beclomethasone can lead to decrease the size of the adenoid and the severity of upper airway obstructive signs and symptoms, as well as eliminating the daily somnolence of children with adenoid hypertrophy.