Author/Authors :
Shakeri، Saeed نويسنده , , Zeighami، Hossein نويسنده Student Research Committee, Fasa University of Medical Sciences, Fasa, Iran , , Salehipour، Mehdi نويسنده , , Beik Mohammadloo، Hossein نويسنده Department of Urology, Shiraz University of Medical Sciences, Shiraz, Iran , , Shakeri، Aria نويسنده University of Toronto, Toronto, Canada , , Shakeri، Arash نويسنده University of Waterloo, Waterloo, Canada , , Zeighami، Shahryar نويسنده Division of Uro-oncology, Department of Urology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran ,
Abstract :
Background: This study compared the early success, complication and patient
satisfaction rates of modified extraperitoneal radical cystectomy (Mainz II urinary diversion)
with standard intraperitoneal radical cystectomy (continent ileocecal urinary diversion) in
a group of patients with muscle invasive urothelial carcinoma of the urinary bladder.
Methods: From September 2009 until November 2013, this randomized study
enrolled 60 patients with muscle invasive transitional cell carcinoma of the urinary
bladder who underwent radical cystectomy and urinary diversion. The patients were
randomly allocated to two groups via block randomization. Group A included 30
patients (28 men and 2 women) who underwent modified small incision extraperitoneal
radical cystectomy with a Mainz II urinary diversion. Group B included 30 patients
(27 men and 3 women) who had classic intraperitoneal radical cystectomy and ileocecal
continent diversion. The data were extracted and analyzed. The patients were followed
for one year after surgery.
Results: Group A patients had a mean age of 61.47±8.63 years. Group B patients
had a mean age of 60.77±6.82 years. There were no statistically significant differences
in blood loss, electrolyte and acid-base abnormalities, and early post- operative
complication rates between the two groups. However, surgical and hospitalization times
were significantly shorter in group A (P < 0.001). In addition, patients were mobilized
earlier and had shorter nothing by moth time. Patient satisfaction rate was significantly
more in group A.
Conclusion: Small incision extraperitoneal radical cystectomy and Mainz II urinary
diversion is a safe, less complicated, effective and more rapid technique with excellent
short term outcome. It seems this technique is a reliable alternative for continent
urinary diversion in selected bladder cancer patients, mainly in those with urethral
involvement.