An efficient one-pot synthesis of new 2-imino-1,3-thiazolidin-4-ones under ultrasonic conditions

A convenient one-pot protocol was developed for the synthesis of 2-imino-1,3-thiazolidin-4-ones by the reaction of amines, isocyanates, aldehydes, and chloroform in the presence of sodium hydroxide under ultrasonic conditions in high yields (75–91%) and shorter reaction times (12–15 min).