Title of article
Efficient sonochemical synthesis of alkyl 4-aryl-6-chloro-5-formyl-2-methyl-1,4-dihydropyridine-3-carboxylate derivatives
Author/Authors
Ruiz، نويسنده , , Enrique and Rodrيguez-Lَpez، نويسنده , , Hortensia and Coro، نويسنده , , Julieta and Niebla، نويسنده , , Vladimir and Rodrيguez، نويسنده , , Alfredo and Martيnez-Alvarez، نويسنده , , Roberto and de Armas، نويسنده , , Hector Novoa and Suلrez، نويسنده , , Margarita and Martيn، نويسنده , , Nazario، نويسنده ,
Issue Information
فصلنامه با شماره پیاپی سال 2012
Pages
6
From page
221
To page
226
Abstract
A facile, efficient and environment-friendly protocol for the synthesis of 6-chloro-5-formyl-1,4-dihydropyridine derivatives has been developed by the convenient ultrasound-mediated reaction of 2(1H)pyridone derivatives with the Vilsmeier–Haack reagent. This method provides several advantages over current reaction methodologies including a simpler work-up procedure, shorter reaction times and higher yields.
Keywords
Vilsmeier–Haack reaction , Ultrasound irradiation , Sonochemistry , 1 , 4-Dihydropyridine Derivatives
Journal title
Ultrasonics Sonochemistry
Serial Year
2012
Journal title
Ultrasonics Sonochemistry
Record number
2190087
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