Choroba Kikuchi i Fujimoto: opis dwóch nowych polskich przypadków i aktualny przegląd piśmiennictwa

Kikuchi-Fujimoto disease (KFD, histiocytic necrotizing lymphadenitis) is benign and self-limited cervical lymphadenopathy with accompanied mild fever. Disorder mostly affects young adults, rarely children mainly in Asia. The etiology of KFD is unknown but it is thought to be an autoimmune or inflammatory process triggered by viral infection in susceptible individuals. The minimal criteria required for the diagnosis of KFD include the presence of paracortical clusters of plasmacytoid dendritic cells admixed with karyorrhectic bodies and crescentic histiocytes. KFD does not require specific treatment except from antipyretics and anti-inflammatory medications. Here we present two new cases of KFD described in Poland together with the review of current literature.