Author/Authors :
Narayana، P V نويسنده Electrochemical Research Laboratory, Department of Chemistry, Sri Venkateswara University, Tirupati- 517 502, Andhra Pradesh, India Narayana, P V , Reddy، T Madhusudana نويسنده Electrochemical Research Laboratory, Department of Chemistry, Sri Venkateswara University, Tirupati- 517 502, Andhra Pradesh, India Reddy, T Madhusudana , Gopal، P نويسنده Electrochemical Research Laboratory, Department of Chemistry, Sri Venkateswara University, Tirupati- 517 502, Andhra Pradesh, India Gopal, P , Raghu، P نويسنده Electrochemical Research Laboratory, Department of Chemistry, Sri Venkateswara University, Tirupati- 517 502, Andhra Pradesh, India Raghu, P , Reddaiah، K نويسنده Electrochemical Research Laboratory, Department of Chemistry, Sri Venkateswara University, Tirupati- 517 502, Andhra Pradesh, India Reddaiah, K , Srinivasulu، M نويسنده Electrochemical Research Laboratory, Department of Chemistry, Sri Venkateswara University, Tirupati- 517 502, Andhra Pradesh, India Srinivasulu, M
Abstract :
This paper deals with the development of an electrochemical sensor base on
Trypan Blue (TB) towards the determination of Dopamine (DA). An electrochemical sensor
was fabricated by the electropolymerization of TB onto the Carbon paste electrode (CPE)
using cyclic voltammetry (CV) technique. The polymerized TB modified CPE
(Poly(TB)MCPE) was characterized using Electrochemical impedance spectroscopy (EIS)
and CV techniques. The sensor Poly(TB)MCPE showed good sensitivity and catalytic
activity in comparison with bare CPE. Electrochemical behaviour of Dopamine (DA) was
investigated in 0.1 M PBS in alkaline medium (pH 8.0) using Poly(TB)MCPE. Moreover,
simultaneous determination of DA in presence of Ascorbic acid (AA) and Uric acid (UA)
was examined using Differential pulse voltammetry (DPV) technique. Several kinetic
parameters such as diffusion coefficient (D0), area of the electrode (A), surface concentration
of modifier on Poly(TB)MCPE (?), limit of detection (LOD) and limit of quantification
(LOQ) were calculated
