Author/Authors :
Tayebi Meybodi، Keyvan نويسنده Department of Neurosurgery, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran Tayebi Meybodi, Keyvan , Taghvaei، Mohammad نويسنده Department of Neurosurgery, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran Taghvaei, Mohammad , Derakhshanrad، Nazi نويسنده Brain and Spinal cord Injury Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran Derakhshanrad, Nazi , Khan، Zahid Hussain نويسنده Brain and Spinal Injuries Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, IR Iran , , Saberi، Hooshang نويسنده Brain and Spinal Cord Injury Research Center (BASIR), Imam Khomeini Hospital Complex, Keshavarz Blvd., Tehran, Iran. Saberi, Hooshang
Abstract :
Neurosurgical interventions have been associated with troublesome bleeding during and after the procedures. There are cases of intractable coagulopathy with life threatening bleeding. In this study, we reported a patient with neurofibromatosis type 1, and huge cranial neurofibroma, associated with massive bleeding after excision. A 22 year-old man was referred to this center with facial deformity due to a large craniofacial neurofibroma. He underwent craniotomy and tumor resection, but intraoperative blood loss was massive, and epidural hematomata developed at the operative site due to coagulopathy. The drains still were draining fresh blood and the patient was severely anemic. After consultation with a hematologist, rFVIIa was administered intravenously to successfully control the bleeding. While using recombinant rFVIIa is life-saving, it should not be a substitute for life saving urgent surgeries and should be cautiously used as a last resort in conjunction with conventional medico-surgical care.
