Title of article :
Production of novel ceramic porous surfaces tailored for bone tissue engineering
Author/Authors :
Michailidis، نويسنده , , Nikolaos and Stergioudi، نويسنده , , Fani and Viglaki، نويسنده , , Konstantina and Chatzinikolaidou، نويسنده , , Maria، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2014
Abstract :
Moderate toughness and poor biological features of ceramics may hinder their application as modern bio-active implants. The paper presents a new, cost-effective, environmentally friendly and simple production method of open-cell calcium phosphate (CP) ceramic foams, by employing powders’ compaction, dissolution and sintering, aiming at producing highly bio-active 3D surface scaffolds. The process parameters were properly adjusted to optimize the quality and structure of CP foams, and samples with various porosity (60–75 vol%) and pore size (0.28–0.50 mm) were fabricated, characterized and mechanically tested. Cell viability, adhesion and proliferation investigations revealed an excellent potential for application in bone tissue engineering.
Keywords :
Biomedical surfaces , powder sintering , cell growth
Journal title :
CIRP Annals - Manufacturing Technology
Journal title :
CIRP Annals - Manufacturing Technology