Effect of Process Variables on Growth Kinetics of Lactose Particles in a Wet Spray Fluidized Bed Granulator

The growth kinetics of Lactose particles in a top spray, small scale fluidized bed granulator is studied experimentally and the effects of binder flow rate and concentration, nozzle air pressure and the fluidizing air temperature on the growth kinetics of granules are studied. The results have been explained by the aid of sequentially main effects of each parameter in the process. The effect of each operating variable has been discussed in detail, qualitatively.