Abstract :
Despite astonishing progress concerning cardiovascular diseases, patients are still suffering
from complications of acute insults. Due to reverse remodeling and improper myocyte
rebuilding, heart failure has become a common problem these days which needs more powerful
myocardial reconstructing strategies. Indeed, no option cases afflicted with non-healing
peripheral vascular diseases; refractory stable and unstable angina is the other field with paucity
of proper treatments. For these cases, stem cell-based therapies became optimistic treatment,
but lack of guideline-based indications regarding stem-cell is still a major problem which limits
application of these cells for such end-stage cases. Here, an outline of appropriateness criteria
for stem cell-based therapy is suggested.
