Author/Authors :
Khosravi، Arezoo نويسنده Atherosclerosis research center, Baqiyatallah University of Medical Sciences, Tehran, Iran , , Sheykhloo، Hadi نويسنده Cardiologist, Department of Cardiology, Cardiovascular Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran , , Karbasi-Afshar، Reza نويسنده Cardiovascular Research Center; Baqiyatallah University of Medical Sciences; Tehran, Iran , , SABURI، Amin نويسنده MD & Researcher, Clinical Injury Research Center & Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran ,
Abstract :
BACKGROUND: Since some degrees of functional mitral regurgitation (MR) may be seen in
patients who are candidate for undergoing isolated aortic valve replacement (AVR), determining
the effectiveness of AVR surgery on MR rate improvement can be effective in designing a
protocol to deal with patients with functional MR. The purpose of this study was to examine the
echocardiographic changes after AVR surgery with a focus on changes in MR.
METHODS: The research was conducted as a before-after observational study on patients
hospitalized in Baqiyatallah Hospital, Tehran, Iran, who were undergone AVR surgery between
2011 and 2012. After selecting the patients and obtaining informed consent to participate in the
project, transthoracic echocardiographic data were collected by a specialist in Cardiology
Echocardiography using ViVid 7 device before and till one week after AVR surgery. The MR rate
was measured using methods; including Color Flow Doppler, PISA, Vena Cava Width and
Effective Regurgitant Orifice.
RESULTS: Finally, the study was conducted on 85 patients (mean age = 56.23 ± 6.10 years, 27
women = 31.8%). Of 21 patients with preoperative MR more than mild (moderate, mild to
moderate), 20 patients (95%) showed at least one degree decrease in MR. Among 64 patients
who had mild MR before the surgery, 29 patients improved (45%), that this difference was
statistically significant (P < 0.001).
CONCLUSION: The study results showed that in patients with preoperative MR degree higher
than mild, after AVR the MR rate improved 24 times more than those who had preoperative MR
degree equivalent to mild and lower. However, these changes are not affected by other
echocardiographic changes and patients demographic characteristics.