Author/Authors :
Lasemi، Zahra نويسنده Department of Chemistry, Firoozkooh Branch, Islamic Azad University, Firoozkooh, Iran. , , Sadeghi، Bahareh نويسنده Hematology Department, Faculty of Medical Science, Tarbiat Modarres University, Tehran, Iran , , Amiri Tavasoli، Fereshteh نويسنده Department of Chemistry, Yazd Branch, Islamic Azad University, P.O. Box 89195-155, Yazd, Iran. ,
Abstract :
Nano silica sulfuric acid as a solid acid, was described to be an effective catalyst for one-pot three-component reaction of
kojic acid, aryl aldehydes and indoles for the preparation of 2-substituted aryl (indolyl) kojic acid derivatives.
High yields, simple operation, easy-work procedure, mild reaction conditions are some advantages of this protocol.
The present method does not involve any hazardous organic solvent. Therefore, this procedure could be classified as green chemistry.
