Author/Authors :
Safari، Javad نويسنده Laboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box: 87317-51167, Kashan, I , , Javadian، Leila نويسنده Laboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box: 87317-51167 Kashan, I.R. Iran. ,
Abstract :
In this paper, Fe3O4-chitosan nanoparticles were prepared by the immobilization of chitosan on the surface of Fe3O4 nanoparticles. Then, the 5-substituted hydantoins were synthesized from the condensation of aldehyde derivatives, ammonium carbonate and zinc cyanide as a well-known cyanating agent by the magnetic Fe3O4-chitosan nanoparticles under neat conditions. Fe3O4-Chitosan nanocatalyst as a renewable hybrid catalyst was easily recovered by an external magnet and reused for 4 times without obvious drop in its catalytic activity. The purpose of this research was to provide an easy method for the synthesis of 5-substituted hydantoins in high yields and short reaction times by a robust and magnetic recoverable catalyst.
