Title of article
The Role of Arginine-Phenylalanine-Amide-Related Peptides in Mammalian Reproduction
Author/Authors
Salehi، Mohammad Saied نويسنده Department of Animal Science, College of Agriculture, Shiraz University, Shiraz, Iran , , Tamadon، Amin نويسنده Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University & Stem Cell and Transgenic Technology Research Center, Shiraz Uni Tamadon, Amin , Jafarzadeh Shirazi، Mohammad Reza نويسنده Department of Animal Science, College of Agriculture, Shiraz University, Shiraz, Iran , , Namavar، Mohammad Reza نويسنده Histomorphometry and Stereology Research Center , Department of Anatomical Sciences, School of Medicine, Shiraz University of Medical Sciences, Shiraz , , Zamiri، Mohammad Javad نويسنده Department of Animal Science, College of Agriculture, Shiraz University, Shiraz, Iran ,
Issue Information
فصلنامه با شماره پیاپی 35 سال 2015
Pages
9
From page
268
To page
276
Abstract
Until 2000 it was believed that gonadotropin-releasing hormone (GnRH) was the
sole regulator of hypophyseal gonadotropes. In 2000, the discovery of a gonadotropin
inhibitory hormone (GnIH) initiated a revolution in the field of reproductive
physiology. Identification of GnIH homologues in mammals, the arginine-phenylalanine-
amide (RFamide)-related peptides (RFRPs), indicated a similar function.
Subsequently, further works conducted in various laboratories worldwide have
shown that these neuropeptides inhibit the hypothalamic-hypophyseal axis. This review
discusses the role of RFRPs in mammalian reproductive processes.
Journal title
International Journal of Fertility and Sterility
Serial Year
2015
Journal title
International Journal of Fertility and Sterility
Record number
2316669
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