Author/Authors :
Sadeghi، Masoumeh نويسنده , , Khalili، Mazdak نويسنده Cardiologist, Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran , , Pourmoghaddas، Masoud نويسنده MD, Professor of Interventional Cardiology, Chamran Heart Hospital, Isfahan University of Medical Sciences, Isfahan , , Talaei، Mohammad نويسنده Medical doctor, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran ,
Abstract :
BACKGROUND: As blood pressure is higher in menopausal women than their peers with
similar Body mass index (BMI), and considering hot flashes as one of the most common
symptoms of menopause, this study was conducted to examine the 24-hour changes of blood
pressure in menopausal women experiencing hot flashes.
METHODS: This cross-sectional study was performed on 26 menopausal 47-53 year-old
women divided into 2 groups of 13. None of them had a history of internal diseases,
hypertension, and hormone medications. Their blood pressure and heartbeat were recorded by a
blood pressure Holter for 24 hours. The data was analyzed through student t-test and analysis of
variance (ANOVA) using SPSS11.5.
RESULTS: Systolic blood pressure of the symptomatic group was significantly higher than the
asymptomatic group during waking hours (P < 0.05). However, the heartbeats and systolic
blood pressure of the symptomatic group were higher than those in the other group in 24 hours.
This difference was not statistically significant (P > 0.05).
CONCLUSION: Similar to hot flashes, the increase in systolic blood pressure may arise from
central sympathetic activity. Peripheral vasoconstriction and increased cardiac output, both
caused by baroreflex dysfunction, might also have been responsible for increments in systolic
blood pressure. Therefore, prospective studies are required to determine how the growing
increase in blood pressure and the prevalence of hypertension differ in both groups.