Author/Authors :
Tavilani، Heidar نويسنده Associate Professor, Urology and Nephrology Research Center, Hamadan University of Medical Sciences, Hamadan, Iran , , Esfahani، Maryam نويسنده PhD Candidate, Department of Clinical Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran ,
Abstract :
Hypertension is a significant health problem worldwide and affects more than 20% of the
adult population. This disorder has an important role in morbidity and mortality of heart and
kidney disease patients. It is believed that essential hypertension is a multifactorial and
polygenic disease; resulting from an interplay between environmental and genetic factors. In
this paper, we will review studies that have inspected new genome screen and introduced a new
viewpoint on candidate genes of essential hypertension. We discuss on polymorphism of
candidate genes which related in the pathogenesis of hypertension and take from experimental
models or knowledge of the pathophysiology. Study on genetic factors of hypertension may be
developing new treatment for these patients.
