Title of article :
Comparison of effects of soft margarine, blended, ghee, and unhydrogenated oil with hydrogenated oil on serum lipids: A randomized clinical trail
Author/Authors :
Mohammadifard، Noushin نويسنده PhD Candidate, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran , , Hosseini، Mohsen نويسنده Associate Professor, Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran , , Sajjadi، Firoozeh نويسنده BS, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. , , Maghroun، Maryam نويسنده Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran , , Boshtam، Maryam نويسنده MSc, Animal Physiology, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. , , Nouri، Fatemeh نويسنده Department of law, Payame Noor University (PNU), PO Box: 19395-3697, IR. Iran ,
Abstract :
BACKGROUND: Trans fatty acids (TFAs) are known as the most harmful type of dietary fats.
Therefore, this study was done to compare the effects of some different oils including
unhydrogenated, blended, ghee, and soft magazine with hydrogenated oil on serum lipid profile
of healthy adults.
METHODS: This study was a randomized clinical trial conducted on 206 healthy participants of
20 to 60 years of age. Subjects were randomly divided into 5 groups and each of them was
treated with a diet containing unhydrogenated oil, ghee, blended oil, soft margarine, or
hydrogenated oil for 40 days. Fasting serum lipids were measured before and after the study.
RESULTS: Compared to hydrogenated oil, total cholesterol (TC) and triglyceride (TG) had a
significant reduction in all groups, LDL-C declined in unhydrogenated oil and soft margarine
groups, and apolipoprotein (Apo) B only in unhydrogenated oil group (all P < 0.05). However,
there was a significant enhancement in ApoA of ghee oil (P < 0.001).
CONCLUSION: Consuming unhydrogenated oil, ghee, soft margarine, and blended oil had some
beneficial effects on serum lipids.
