Abstract :
In spite of great progress in the treatment of acute coronary syndrome (ACS) events in
reperfusion era, patients are still at risk for development of heart failure due to negative
remodeling. Thus, the importance of regenerative therapies in parallel with reperfusion
strategies is fundamental. A key feature in this case is obtaining the most appropriate door-tocardiac
regeneration (D2CR) time. This golden time in which fresh stem cells can invade scareprone
tissue could be defined as door-to-cardiac stem cell (D2CSC) plus door-to-cardiac
regeneration (D2CR) time. Application of stem cells in this golden time allows comprehensive
regeneration and reconstruction. Therefore, the aim of this study was to plan the outlines of
simultaneous application of cellular and vascular reconstruction strategies.
