Title of article
Gastrointestinal effects of Nigella sativa and its main constituent, thymoquinone: a review
Author/Authors
-، - نويسنده Neurogenic Inflammation Research Centre and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Iran Shakeri, Farzaneh , -، - نويسنده Neurogenic Inflammation Research Centre and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Iran Gholamnezhad, Zahra , -، - نويسنده Department of Medical and Toxicological Critical Care, Paris-Diderot University, INSERM U1144, Paris, France Mégarbane, Bruno , -، - نويسنده Department of Physiology and Pharmacology, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran Rezaee, Ramin , -، - نويسنده Neurogenic Inflammation Research Centre and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Iran Boskabady, Mohammad Hosein
Issue Information
دوماهنامه با شماره پیاپی 0 سال 2016
Pages
12
From page
9
To page
20
Abstract
-
Abstract
Gastrointestinal (GI) diseases affect a large number of people all over the world. Uncontrolled acid secretion and occurrence of gastric ulcers are common disorders of GI tract which pose serious problems to human health. Many synthetic drugs have been used to treat GI disorders but a definite cure has not been discovered so far and the available medications cause several side effects. Nigella sativa (N. sativa) (Ranunculacea) has several therapeutic effects which are attributed to its constituents like nigellicine, nigellidine, thymoquinone, dithymoquinone, thymol and carvacrol. Several beneficial pharmacological properties of this plant such as anti-oxidant, anti-bacterial, anti-histaminic, anti-hypertensive, hypoglycemic, anti-fungal, anti-inflammatory, anti-cancer and immunomodulatory effects were reported and different therapeutic properties such as reliving bronchial asthma, jaundice, hydrophobia, paralysis, conjunctivitis, piles, skin diseases, anorexia, headache, dysentery, infections, obesity, back pain, hypertension and gastrointestinal problems, have been described for the seeds of N. sativa and its oil. The present review provides a detailed summery of scientific researches regarding gastrointestinal effect of N. sativa and its main constituent, thymoquinone.
Journal title
Avicenna Journal of Phytomedicine AJP)
Serial Year
2016
Journal title
Avicenna Journal of Phytomedicine AJP)
Record number
2356645
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