Comparison of hemodynamic stability, bleeding, and vomiting in propofol-remifentanil and isoflurane-remifentanil techniques in septorhinoplasty surgery

Background: Due to prevalence of septorhinoplasty surgery in Iran and in the world, and the importance of anesthetic technique in bleeding and conducting an accurate and uncomplicated surgery, we decided to compare the hemodynamic stability, bleeding and recovery time with the two techniques in the surgical anesthetic propofol and isoflurane in septorhinoplasty. Material and methods: This is a prospective, double-blind, and randomized trial study in which enrolled 60 patients undergoing septorhinoplasty surgery in class ASA I and ASA II. The patients were divided into two groups of 30 anesthetized with propofol and isoflurane. Then hemodynamics changes, bleeding and surgeon satisfaction were evaluated and recorded for both groups during surgery and after (recovery). Data were analyzed using SPSS V18. Results: Of 60 patients, 40 were females and 20 males, with a mean age of 25 ± 2.3 years old. The patients had no underlying disease, and their anesthesia and surgical characteristics were similar. Bleeding mean was 155 ± 14.3 ml in the propofol group, and 164.12 ± 18.24 ml in the isoflurane group, which was not significantly different in terms of bleeding . There was a significant difference between recovery time and incidence of nausea and vomiting between the two groups (P < 0.05), therefore the average recovery time was 20.23 ± 3.28 in the propofol group min and 25.13 ± 4.72 min in the isoflurane group. Intraoperative hemodynamics was not significantly different between the two study groups (P > 0.05). The average duration of surgery in both groups was 179 ± 21 min. Conclusion: The findings of this study showed that there were no significant differences between bleeding and hemodynamic stability in the two methods, and anesthesia and induction in both techniques can be used in septorhinoplasty surgery. However, since the recovery time was short and incidence of nausea and vomiting in anesthesia with propofol was less than isoflurane, it seemed that the use of propofol was better than isoflurane.