• Title of article

    Myotonic disorders: A review article

  • Author/Authors

    Hahn، Chris نويسنده Department of Neurology, Brigham and Women’s Hospital, Harvard Medical School, ‎Boston, USA Hahn, Chris , Salajegheh، Mohammad Kian نويسنده Department of Neurology, Brigham and Women’s Hospital, Harvard Medical School, ‎Boston, USA Salajegheh, Mohammad Kian

  • Issue Information
    فصلنامه با شماره پیاپی 0 سال 2016
  • Pages
    8
  • From page
    46
  • To page
    53
  • Abstract

    The myotonic disorders are a heterogeneous group of genetically determined diseases that are unified by the presence of myotonia, which is defined as failure of muscle relaxation after activation. The presentation of these disorders can range from asymptomatic electrical myotonia, as seen in some forms of myotonia congenita (MC), to severe disability with muscle weakness, cardiac conduction defects, and other systemic features as in myotonic dystrophy type I (DM1). In this review, we describe the clinical features and pathophysiology of the different myotonic disorders, their laboratory and electrophysiologic findings and briefly review the currently available treatments.

  • Journal title
    Iranian Journal of Neurology
  • Serial Year
    2016
  • Journal title
    Iranian Journal of Neurology
  • Record number

    2384948