Author/Authors :
Hosseeini، S نويسنده Aliasghar Hospital, Iran University of Medical Sciences, Tehran, Iran , , Ansari، Sh نويسنده Assistant professor of Pediatrician, Oncologist, Ali-Asghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran , , Kalantar، E نويسنده Immunology Department, Iran University of Medical Sciences, Tehran, Iran , , Sabzechian، M نويسنده Aliasghar Hospital, Iran University of Medical Sciences, Tehran, Iran , , Alibeik، A نويسنده Aliasghar Hospital, Iran University of Medical Sciences, Tehran, Iran , , Dorgalaleh، A نويسنده hematology and blood transfusion Department, Allied Medical School, Tehran Unversity of Medical Sciences, Tehran, Iran ,
Abstract :
Background
Autoimmune hemolytic anemia is a hematologic
disorder that is rarely observed in infants and young
children. Most of the cases are associated with viral
or bacterial infections. In some cases, AIHA can be
characterized by a chronic course and an
unsatisfactory control of hemolysis, thus requiring
prolonged immunosuppressive therapy.
Case report
Especially in children younger than 2 years of age,
the clinical course of the disease may show either
resistance to steroids or dependence on high-dose
steroids. We report here an infant fatal autoimmune
Conclusion
This case suggests that investigation for the presence
of CMV infection in infantile AIHA should be
considered. Severe hemolysis is rare but could be a
potentially life-threatening complication of CMV
infection described mostly in immune compromised
adults and children
