Author/Authors :
Onsori، Habib نويسنده Department of Cell & Molecular Biology, Marand Branch, Islamic Azad University, Marand, Iran. Onsori, Habib , Rahmati، Mohammad نويسنده , , Fazli، Davood نويسنده Department of Physiology, Payame Noor University, Marand, Iran. Fazli, Davood
Abstract :
Mutations in the Connexin 26 (Cx26) gene are a common cause of hereditary hearing loss in different populations. In the present study, an Iranian patient with bilateral hearing loss underwent molecular analysis for the causative mutation. DNA studies were performed for the Cx26 gene by PCR and sequencing methods. We describe a novel compound heterozygous mutation (35delG, 363delC) in the Cx26 gene that is strongly associated with congenital non-syndromic hearing loss (NSHL).
