Combination Antifungal Treatment for Sino-Orbito-Cerebral Mucormycosis: A Case Report

Introduction: Invasive mucormycosis is an opportunistic fungal infection in patients with predisposing factors. Case Presentation: We report a case of sino-orbito-cerebral mucormycosis in a diabetic patient successfully treated with combination of liposomal amphotericin B (L-AMB) and posaconazole. Conclusions: Clinicians should be alert of the clinical presentation of this fulminant fungal infection and notice that prompt diagnosis can be life-saving. Moreover, combination regimens may be considered as an option of treatment failure.