Author/Authors :
Karimi، Narges نويسنده Department of Neurology, Clinical Research Development Unit of Bou Ali Sina Hospital, Mazandaran University of Medical Sciences, Sari, Iran Karimi, Narges , Sharifi، Athena نويسنده Department of Neurology, Clinical Research Development
Unit of Bou Ali Sina Hospital, Mazandaran University of Medical
Sciences, Sari, IR Iran , , Zarvani، Ashraf نويسنده Department of Neurology, Clinical Research Development
Unit of Bou Ali Sina Hospital, Mazandaran University of Medical
Sciences, Sari, IR Iran , , Cheraghmakani، Hamed نويسنده Department of Neurology, Clinical Research Development
Unit of Bou Ali Sina Hospital, Mazandaran University of Medical
Sciences, Sari, IR Iran ,
Abstract :
Context: Chronic inflammatory demyelinating polyradiculopathy (CIDP) is an acquired and autoimmune neuropathy, characterized by a chronic, rapidly progressive, symmetric weakness. In children, abnormal gait is as a first symptom of muscle weakness.
Evidence Acquisition: The diagnosis of CIDP is on the basis of clinical characteristics, electrodiagnostic that shows the severity of the disease, lumbar puncture and spine magnetic resonance imaging (MRI).
Results: The first-line treatments in childhood CIDP are intravenous immunoglobulin (IVIG), corticosteroids, and plasmapheresis. Response to first-line therapies is usually satisfactory; nevertheless, recommendations regarding the choice of second-line therapy can only be prepared on the basis of the existing practice described in some of the case reports.
Conclusions: This review demonstrated the clinical presentation, diagnosis, and treatment of childhood CIDP.
