Efficient Synthesis of Dihydropyrimidine and Amidoalkyl Naphthol Derivatives Using Zinc Chloride-Based Deep Eutectic Systems as Solvent & Catalyst

Dihydropyrimidine and amidoalkyl naphthol derivatives have been prepared efficiently in a one-pot synthesis using ZnCl2/urea and ZnCl2/acetamide deep eutectic systems as reaction medium and homogeneous catalyst. This method offers some advantages such as simple procedure, inexpensive solvent and catalyst and good yields of the final products in short reaction times. The use of non-toxic and environmentally benign catalyst and solvent system are the main remarkable features of this procedure.