Title of article :
The Protective Effect of Conditioning on Noise-Induced Hearing Loss Is Frequency-Dependent
Author/Authors :
Pourbakht، Akram نويسنده Department of Audiology, Faculty of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran , , Imani، Azadeh نويسنده Department of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran. Imani, Azadeh
Issue Information :
ماهنامه با شماره پیاپی 0 سال 2012
Pages :
6
From page :
664
To page :
669
Abstract :

We compared the extent of temporary threshold shift (TTS) and hair cell loss following high level 4 kHz noise exposure with those preconditioned with moderate level 1 and 4 kHz octave band noise. Fifteen Male albino guinea pigs (300- 350 g in weight) were randomly allocated into three groups: those exposed to 4 kHz octave band noise at 102 dB SPL (group 1, n=5); those conditioned with 1 kHz octave band noise at 85 dB SPL, 6 hours per day for 5 days, then exposed to noise (group 2, n=5); those conditioned with 4 kHz octave band noise at 85 dB SPL, then exposed to noise (group 3, n=5). An hour and one week after noise exposure, threshold shifts were evaluated by auditory-evoked brainstem response (ABR) and then animals were euthanized for histological evaluation. We found that TTS and cochlear damage caused by noise exposure were significantly reduced by 1 kHz and 4 kHz conditioning (P

Journal title :
Acta Medica Iranica
Serial Year :
2012
Journal title :
Acta Medica Iranica
Record number :
2389604
Link To Document :
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