Author/Authors :
Pourmahmoodian، Hossein نويسنده Department of Neurology, Iranian Center of Neurological Research, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Pourmahmoodian, Hossein , Ghelichnia Omrani، Hossein Ali نويسنده Department of Neurology, Iranian Center of Neurological Research, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Ghelichnia Omrani, Hossein Ali , Harrirchian، Mohammad Hossein نويسنده Department of Neurology, Iranian Center of Neurological Research, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Harrirchian, Mohammad Hossein , Ghabaee، Mojdeh نويسنده Iranian Center of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, IR Iran , , Zamani، Babak نويسنده Assistant Professor of Neurology, Department of Neurology, Rasoul-e-Akram Hospital , , Ghaffarpour، Majid نويسنده Professor of Neurology, Iranian Center of Neurological Research ,
Abstract :
Primary angiitis of the central nervous system (PACNS) is an idiopathic disorder (vasculitis) restricted to the central nervous system (CNS). It often presents with focal neurological deficits suggesting stroke or a combination of confusion and headache. We herein report three cases with various combinations of fever, partial seizure, encephalopathy, paresis, headache and ataxia. One of them was initially treated as herpes simplex meningoencephalitis, but further investigations revealed primary angiitis. Primary angiitis of the CNS has protean manifestations and should always be considered in patients suspicious to have CNS infection or stroke, particularly who does not respond to the routine treatments. Clinical data, exclusion of differential diagnoses and typical angiography seem to be enough to justify the diagnosis in the majority of cases.
