Title of article
Human papilloma virus and esophageal squamous cell carcinoma.
Author/Authors
Haeri، Hayedeh نويسنده Imam Khomeini Hospitals’ complex, Dept. of Pathology, Tehran University of Medical Science, Tehran , , Mardany، Omid نويسنده Department of Pathology AND Cancer Research Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Mardany, Omid , Asadi-Amoli، Fahimeh نويسنده , , Shahsiah، Reza نويسنده ,
Issue Information
ماهنامه با شماره پیاپی 0 سال 2013
Pages
4
From page
242
To page
245
Abstract
Human papilloma virus (HPV) has been suggested as an etiology of esophageal squamous cell carcinoma (SCC). The aim of this study was to investigate the prevalence of HPV infection in esophageal SCCs in our region with strict contamination control to prevent false positive results. Thirty cases of esophageal squamous cell carcinomas were chosen by simple random selection in a period of two years. PCR for target sequence of HPV L1 gene was performed on nucleic acid extracted from samples by means of GP5+/GP6+ primers. All tissue samples in both case and control groups were negative for HPV-DNA. Although the number of cases in this study was limited, the contribution of HPV in substantial number of esophageal SCCs in our region is unlikely.
Journal title
Acta Medica Iranica
Serial Year
2013
Journal title
Acta Medica Iranica
Record number
2390046
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