Title of article
Effects of Coenzyme Q10 on LDL Oxidation In vitro
Author/Authors
Ahmadvand، Hassan نويسنده , , Mabuchi، Hiroshi نويسنده Department of Lipidology, Graduate School of Medical Science, Kanazawa University, Japan. Mabuchi, Hiroshi , Nohara، Atsushi نويسنده Department of Lipidology, Graduate School of Medical Science, Kanazawa University, Japan. Nohara, Atsushi , Kobayahi، Junji نويسنده Department of Lipidology, Graduate School of Medical Science, Kanazawa University, Japan. Kobayahi, Junji , Kawashiri، Masa-aki نويسنده Department of Lipidology, Graduate School of Medical Science, Kanazawa University, Japan. Kawashiri, Masa-aki
Issue Information
ماهنامه با شماره پیاپی 0 سال 2013
Pages
7
From page
12
To page
18
Abstract
Coenzyme Q10, a lipid soluble benzoquinone, has excellent antioxidant and membrane stabilizing properties in the cardiac tissue. The present study investigated the effects of coenzyme Q10 on in vitro LDL oxidation quantitavely. The formation of conjugated dienes, malondialdehyde (MDA) and electrophoretic mobility were monitored as markers of the oxidation of LDL, respectively. Coenzyme Q₁₀ showed a decrease the formation of conjugated dienes and MDA, respectively, against oxidation in vitro. Coenzyme Q₁₀ also reduced electrophoretic mobility of the oxidized human LDL. Thus, results showed that the coenzyme Q10 exhibits strong antioxidant activity in CuSO₄-mediated oxidation of LDL (P
Journal title
Acta Medica Iranica
Serial Year
2013
Journal title
Acta Medica Iranica
Record number
2390093
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