Author/Authors :
Shahrokh Tehrani Nejad، Ensieh نويسنده , , Hosein Rashidi، Batool نويسنده Department of Obstetrics and Gynecology, Tehran University of Medical Sciences, Tehran, Iran. , , Larti، Atefeh نويسنده Department of Obstetrics and Gynecology, Tehran University of Medical Sciences, Tehran, Iran. , , Ezabadi، Zahra نويسنده Department of Epidemiology and Reproductive Health, Reproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran , , Jahangiri، Nadia نويسنده Department of Endocrinology and Female Infertility at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, T , , Azimi Nekoo، Elham نويسنده Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran ,
Abstract :
Background: Endometriosis is one of the most challenging diseases that constitute 20% - 40% of women searching for their infertility diagnosis. Objective: This study was undertaken in order to compare the outcome of in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) in women with endometriosis, and tubal factor infertility as controls. Materials and Methods: From 2005 to 2006 a retrospective study was carried out in patients with endometriosis (n=80) and tubal infertility (n=57) after treatment with IVF/ICSI. The main outcome measures were ovarian responsiveness, quality of oocytes, implantation, pregnancy and ongoing pregnancy rates. Appropriate statistical analysis was performed using ?2 and student t-tests. Results: No differences were found in mean number of ampoules of hMG, duration of hMG injection, number of M?? oocytes, number of embryo transferred, and rates of implantation, pregnancy, ongoing pregnancy and twin birth between women with endometriosis and tubal infertility and also between women with stages I/II or those with stages III/IV disease with women with tubal factor infertility. Conclusion: Our results suggest that endometriosis does not seem to have adverse effect on outcome of IVF/ ICSI as compared with tubal infertility.
