Author/Authors :
ZANDIEH، FARIBORZ نويسنده , , Mirsaed Ghazi، Bahram نويسنده Department of Asthma, Allergy and Immunology, Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran. Mirsaed Ghazi, Bahram , Izadi، Anahita نويسنده Department of Infectiousn Diseases, Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran. Izadi, Anahita , Gharegozlu، Mohammad نويسنده Department of Infectiousn Diseases, Children Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Gharegozlu, Mohammad , Aghajani، Motahareh نويسنده Department of Asthma, Allergy and Immunology, Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran. Aghajani, Motahareh , Sheikh، Mahdi نويسنده Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, IR Iran ,
Abstract :
Papillon-Lefevre syndrome (PLS) is a very rare genetic syndrome, and fewer than 500 cases have been reported in the world. Patients exhibit typical cutaneous involvement with hyperkeratosis, especially on the soles and palms, and early shedding of primary teeth. Internal organ involvements, such as liver abscesses, have been described in case reports. This communication represents the first time that genetically documented PLS with footprints of mycobacterium tuberculosis in liver and kidney is reported. T-Lymphocyte transformation Test with PHA was abnormal in this patient.
