Author/Authors :
Miri، Mojtaba نويسنده Department of Neurosurgery, Emam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran , , Ghanaati، Hossein نويسنده , , Salamati، Payman نويسنده , , Ebrahimi Nik، Hojat نويسنده Advanced Diagnostic and Interventional Radiology Research
Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical
Sciences, Tehran, Iran , , Jalali، Amir-Hossein نويسنده Assistant Professor of Psychiatry, Mental Health Research Center, Tehran Psychiatric Institute, Tehran University of Medical Sciences and Health Services, Tehran, Iran. , , Saeednejad، Mina نويسنده Department of Radiology, Islamic Azad University, Tehran Medical Branch, Tehran, Iran. Saeednejad, Mina , Firouznia، Kavous نويسنده ,
Abstract :
Rupture of the intracranial aneurysms is associated with a high
risk of bleeding and a high incidence of mortality if left untreated.
The aim of this study is to report our experience in managing
intracranial aneurysms using coil embolization and to report the 6-month
follow-up outcome of the patients. From January 2010 to December 2012, a
series of 90 nonrandomized consecutive patients (mean age: 44.6 ± 14.9
years) with intracranial aneurysms underwent endovascular coil
embolization in our center. We excluded patients with dissecting, blood
blister-like, or false aneurysms. All patients were evaluated by
four-vessel angiography to determine the shape, size, number and
location of the aneurysms. We recommended a six-month follow-up control
angiography. However, only 38 of them participated in this follow-up
imaging. The data were analyzed by chi-square, fisher exact and t-tests
and alpha was considered lower than 5%. Immediately after the procedure,
the total occlusion was seen in 76 (86.4%), subtotal occlusion in six
(6.8%), and partial occlusion in six patients (6.8%). There was no
significant relationship between the aneurysm size, aneurysm neck size,
and location of the aneurysm with total or subtotal occlusions. Eleven
patients (12.5%) experienced some complication during the procedure
including two tears, three focal neurological signs, three vision
disturbances, and three bleedings in the aneurysm. Major complications
were significantly higher in the posterior aneurysm compared to the
anterior ones (55.6% versus 44.4% of the major complications; P value =
0.015). Among patients who underwent control angiography, 34 patients
(89.4%) had no change, two (5.3%) had new growth and two (5.3%) had
widening of the neck after 6 months follow-up. Although aneurysms that
remained unchanged after six months follow-up angiography had total
occlusion after the procedure, it was 50% for aneurysms that had any
changes in 6 months follow-up angiography (P value = 0.01). Coil
embolization showed successful outcomes in the treatment of intracranial
aneurysms with a low complication rate.
