Title of article
Evaluation of the effects of magnesium supplement in primary and secondary preventions of nephrolithiasis: a systematic review
Author/Authors
-، - نويسنده Department of Pediatric, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Azarfar, Anoush , -، - نويسنده Department of Pediatric, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Esmaeili, Mohammad , -، - نويسنده Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Tousi, Nayere , -، - نويسنده Department of Pediatric, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Naseri, Mitra , -، - نويسنده Department of Pediatric, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Ghane, Fatemeh , -، - نويسنده Clinical Research Development Unit, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Ravanshad, Yalda , -، - نويسنده Department of Clinical Toxicology, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran. Alizadeh, Anahita
Issue Information
فصلنامه با شماره پیاپی سال 2016
Pages
5
From page
18
To page
22
Abstract
-
Abstract
Introduction: The role of magnesium supplement to prevent primary and/or secondary kidney stones has not been fully determined. The aim of this study is to evaluate the effects of magnesium supplement in modifying urinary risk factors of recurrent kidney stones.Method: We searched MEDLINE, Scopus, and Google Scholar databases on December 7, 2014 and reference lists of systematic reviews and randomized, controlled trials. Among the initial 282 articles found by our search strategy and hand searching, we found eight English-language studies were eligible for our study.Result: Magnesium supplementation could be beneficial in nephrolithiasis prevention through increasing urinary magnesium, citrate, and calcium while declining urinary oxalate. In pediatric patients, the results were more prominent and could decline urinary oxalate up to 90% of the baseline.Conclusions: Magnesium supplementation could be beneficial, especially with potassium-citrate combination. However, due to the low number of well-designed randomized controlled trials, especially in pediatrics, the conclusions of this study need further confirmation.
Journal title
Reviews in Clinical Medicine
Serial Year
2016
Journal title
Reviews in Clinical Medicine
Record number
2392705
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