Author/Authors :
Maziar، Asghar نويسنده Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IR Iran , , Shahbazi-Gahrouei، Daryoush نويسنده , , Tavakoli، Mohammad Bagher نويسنده , , Changizi، Vahid نويسنده Department of Radiology and Radiotherapy Technology, School of Allied Health Sciences, Tehran University of Medical Sciences, Tehran, Iran. Changizi, Vahid
Abstract :
Background:
Using hair samples to analyze the trace element concentrations is of interest among many researchers. X-ray fluorescence (XRF) and X-ray diffraction (XRD) are the most common methods in studying the structure and concentration of elements of tissues and also crystalline materials, using low energy X-ray.
Objectives:
In the present study, the detection ability of Wave Length X-ray Fluorescence (WLXRF) of breast cancer at early stages was evaluated and the results were compared with other routine modalities such as mammography.
Materials and Methods:
Hair samples of 54 women (including 27 healthy and 27 patients) with average age of 52.03 ± 11.44 years were analyzed. All the sample donors were Iranian women. For the measurements Wave Length X-ray Fluorescence (WLXRF) method was used.
Results:
Trace elements in healthy individuals were higher than those in cancer patients. In addition, sensitivity of the used method (WLXRF) was 96% compared to mammography (77%) as a gold standard for breast cancer detection.
Conclusions:
Trace elements in healthy individuals were higher than cancer patients and it seems that WLXRF may be used as a safe, low cost and reliable method with sensitivity higher than those of the other two relevant methods, XRD and mammography.
