• Title of article

    Who is One Locus Mismatched sibling Donor, Who is not?

  • Author/Authors

    Ostadali، Mohammadreza نويسنده Hematology- Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran Univer Ostadali, Mohammadreza , Ghashghaie، Andisheh نويسنده Hematology- Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran Univer Ghashghaie, Andisheh , Ghavamzadeh، Ardeshir نويسنده ,

  • Issue Information
    دوفصلنامه با شماره پیاپی 0 سال 2009
  • Pages
    3
  • From page
    34
  • To page
    36
  • Abstract

    The most important factor in donor-recipient matching for hematopoietic stem cell transplantation is their HLA typing. For many patients, we can not find a full-matched donor. In high risk patients, one locus  mismatched related donors are suitable alternatives. (1, 2) Since the matching of patients and their siblings usually is based on low resolution HLA typing, the matching of one locus mismatched  siblings is always prone to catastrophic errors.   The following cases clearly demonstrate the possible pitfalls and highlight the importance of the HLA typing of parents in the matching of patients and their full-matched and one locus, mismatched siblings.

  • Journal title
    International Journal of Hematology-Oncology and Stem Cell Research (IJHOSCR)
  • Serial Year
    2009
  • Journal title
    International Journal of Hematology-Oncology and Stem Cell Research (IJHOSCR)
  • Record number

    2393752