Author/Authors :
Yang، Biao نويسنده , , You، Xin نويسنده Department of Abdominal Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, China , , Yuan، Min lan نويسنده Psychiatry Centre, West China Hospital, West China Medical School, Sichuan University, Chengdu, China , , Qin، Tian Qiang نويسنده Chinese Evidence-Based Medicine Centre, West China Hospital, West China Medical School, Sichuan University, Chengdu, China , , Duan، Lin Jia نويسنده Department of Radiology, West China Hospital, West China Medical School, Sichuan University, Chengdu, China , , He، Jiao نويسنده Department of Radiology, West China Hospital, West China Medical School, Sichuan University, Chengdu, China , , Fei، Ze Jun نويسنده Department of Radiology, West China Hospital, West China Medical School, Sichuan University, Chengdu, China , , Zhou، Ding-Xuan نويسنده , , Zan، Rui Yu نويسنده Department of Abdominal Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, China , , Liao، Zheng Yin نويسنده Department of Abdominal Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, China ,
Abstract :
The prognosis for hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) is extremely poor. This study aimed to evaluate the safety and effectiveness of transarterial ethanol ablation (TEA) for the treatment of HCC with PVTT. Patients were treated with TEA for PVTT under cone-beam computed tomography and traditional transarterial chemoembolization (TACE) with epirubicin for intrahepatic lesions. Seventeen men were successfully treated with TACE plus TEA. The mean overall survival was 18.3 ± 9.0 months (95% CI: 13.7 - 3.0 months). The quality of life (QoL) score increased from 56.9 ± 15.7 before the procedure to 88.5 ± 11.7 at 4 weeks after the procedure. Lipiodol accumulation grades of 3, 2, 1, and 0 were obtained in 3 (17.6%), 8 (47.1%), 6 (35.3%), and 0 (0%) patients, respectively. TEA is a safe and effective method for treating patients with PVTT, offering advantages for QoL, response rate after TEA, and OS.
