Author/Authors :
Hashemi، Masoud نويسنده Dept. of Anesthesiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran Hashemi, Masoud , Jalili، Parviz نويسنده Anesthesiology Research Center, Mofid Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran , , Mennati، Shirin نويسنده Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran , , Koosha، Alireza نويسنده Anesthesiology Research Center, Mofid Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran , , Rohanifar، Ramin نويسنده Anesthesiology Research Center, Mofid Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran , , Madadi، Firouz نويسنده Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran , , Razavi، Seyed Sajad نويسنده Department of Anesthesiology, Mofid Pediatric Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran , , Taheri، Farinaz نويسنده Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran ,
Abstract :
Knee osteoarthritis (KOA) is a common disabling disease. Limited studies have demonstrated that prolotherapy with dextrose or with prolozone can be helpful in the treatment of patients with KOA. In the current study, we compared the results between these two treatment methods. In the current randomized clinical trial, 80 patients with mild to moderate KOA were randomly assigned equally into two groups (ozone group and dextrose group). In each group, injections were repeated three times with 10-day intervals. Before the treatment and 3 months after the injections, the pain intensity was measured by using a visual analogue scale and the Western Ontario and McMaster university arthritis index scores. Finally, the results were compared between the two groups. In the two groups, the pain intensity and WOMAC scores significantly decreased and increased, respectively (P < 0.001). However, there was no significant difference between the two groups. Prolotherapy with dextrose and with prolozone result in the same pain relief or functional improvement in patients with mild to moderate KOA.
