Author/Authors :
Fahimzad، Alireza نويسنده , , Karimi، Abdollah نويسنده , , Rafiei Tabatabaei، Sedigheh نويسنده Pediatric Infections Research Center, Department of Pediatric Infectious Diseases, Shahid Beheshti University of Medical Sciences , , Armin، Shahnaz نويسنده , , Mansour Ghanaei، Roxana نويسنده Pediatric Infections Research Center, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , , Fallah، Fatemeh نويسنده , , Shiva، Farideh نويسنده Pediatric Infections Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences , , Roshanzamir، Fatholla نويسنده Pediatric Surgery Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , , Mostafavi، Nasser نويسنده Pediatrics Department, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, IR Iran , , Sayyahfar، Shirin نويسنده Department of Pediatric Rheumatology, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , , Sedighi، Iraj نويسنده Department of Pediatric,Hamadan University of Medical sciences, Hamadan, Iran. , , Soleimani، Gholamreza نويسنده Research Center for Children and Adolescents, Zahedan University of Medical Sciences, Zahedan, IR Iran , , Kahbazi، Manijeh نويسنده Department of Pediatric, Arak University of Medical
Sciences, Arak, IR Iran , , Nikfar، Roya نويسنده Infectious and Tropical Diseases Research Center, Aboozar Childrens Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran Nikfar, Roya , Abedini، Masomeh نويسنده Department of Pediatrics, Faculty of Medicine, Sanandaj University of Medical Sciences, Sanandaj, IR Iran , , Arjmand، Reza نويسنده Pediatric Infectious Diseases Research Center (PIRC),
Mofid Children Hospital, Shahid Beheshti University of Medical
sciences, Tehran, IR Iran , , Abdollah Gorji، Fatemeh نويسنده , , Safaei، Nava نويسنده Medical Faculty, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , , Noroozi، Shokofeh نويسنده Medical Faculty, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , , Gharooei، Azadeh نويسنده Medical Faculty, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran ,
Abstract :
Hydatid disease (HD) is still an important health hazard in the world. This disease is a parasitic infestation endemic in many sheep- and cattle-raising areas such as Iran. This study aimed to review the clinical manifestations, laboratory aspects, imaging findings, and management of HD. Data were collected from the medical records of patients diagnosed with HD in eight referral hospitals in different provinces of Iran from 2001 to 2014. Overall, 161 children at a mean age of 9.25 ± 3.37 years (age range = 1 - 15 years old) hospitalized with a definite diagnosis of the hydatid cyst between 2001 and 2014 were studied. The male-to-female ratio was 1.6:1. The most commonly involved organ was the lung (67.1%), followed by the liver (44.1%) and a combined liver and lung involvement was found in 15.5% of the patients. The cysts were found more frequently in the right lobe of the liver and lung than in the left lobe. The most frequent complaints were fever (35.4%) and abdominal pain (31.7%), and the most frequent sign was an abdominal mass in the liver involvement and cough in the lung involvement. There was a high eosinophil count (> 500/micL) in 41% of our cases. A high erythrocyte sedimentation rate (> 30) or positive C-reactive protein (based on the qualitative method) was found in 18.6% of the patients and leukocytosis > 15000/micL in 29.2% of the children. Ultrasonography was the main imaging test, with an accuracy rate of 96%, and chest X-ray was helpful in 88.6% of the cases. Surgery was performed in 89% of the patients, and selective patients underwent percutaneous aspiration-injection-reaspiration drainage or medical treatment. The lung was the most commonly involved organ in the children recruited in the present study. Given the high probability of multiple organ involvement, we recommend that patients with HD be assessed via ultrasonography and chest X-ray. In endemic regions, unexplained eosinophilia should be considered as a parasitic disease like HD and its complications.
