Author/Authors :
Shahraki Zahedani، Shahram نويسنده Department of Microbiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, IR Iran , , Moghadampour، Mehdi نويسنده Department of Microbiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, IR Iran , , Bokaeian، Mohammad نويسنده , , Ansari-Moghaddam، Alireza نويسنده Department of Epidemiology and Biostatistics, Health Promotion Research Center, Faculty of Health, Zahedan University of Medical Sciences, Zahedan Ansari-Moghaddam, Alireza
Abstract :
Background
Resistance to various classes of antibiotics is common among extended-spectrum beta-lactamases (ESBLs)-producing bacteria.
Objectives
To determine the antibiotic resistance pattern of ESBLs-producing K. pneumoniae clinical isolates from Zahedan.
Methods
In this sectional-descriptive study, susceptibility of 51 ESBLs-producing K. pneumoniae isolates to 18 antimicrobial agents was determined.
Results
All isolates were resistant to cefotaxime, cefpodoxime and amoxicillin as well as susceptible to colistin sulfate. Also, most isolates were resistant to trimethoprim/sulfamethoxazole and aztreonam.
Conclusions
Our findings demonstrated that the rate of resistance to beta-lactams, sulfonamides, tetracyclines, aminoglycosides and fluoroquinolones in ESBLs-producing K. pneumoniae isolates is high in Zahedan.
